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Journal of Intensive Care Medicine
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What's this?

Vasopressin: Applications in Clinical Practice

Peter C. Dyke, II, MD

Department of Child Health, Division of Pediatric Critical Care/Pediatric Anesthesiology, University of Missouri-Columbia

Joseph D. Tobias, MD

Department of Child Health and the Department of Anesthesiology, Division of Pediatric Critical Care/Pediatric Anesthesiology, University of Missouri-Columbia, tobiasj{at}health.missouri.edu

Arginine vasopressin is a peptide produced in the posterior pituitary whose primary physiologic role is fluid homeostasis. Recent investigations have demonstrated a therapeutic role for arginine vasopressin in adult cardiac arrest as well as adult and pediatric vasodilatory shock. We review the physiology of arginine vasopressin and examine the supporting data behind the developing clinical applications of this naturally produced peptide.

Key Words: vasopressin • vasodilatory shock • hypotension • cardiopulmonary resuscitation

Journal of Intensive Care Medicine, Vol. 19, No. 4, 220-228 (2004)
DOI: 10.1177/0885066604265246
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