This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Altintop, L. Articles by Akpolat, T. Search for Related Content PubMed PubMed Citation Articles by Altintop, L. Articles by Akpolat, T. Social Bookmarking                   What's this?

In Acute Organophosphate Poisoning, the Efficacy of Hemoperfusion on Clinical Status and Mortality

Ondokuz Mayis University, School of Medicine, Departments of Internal Medicine,, Samsun, Turkey, leventaltintop{at}hotmail.com

Dursun Aygun, MD

Ondokuz Mayis University, School of Medicine, Departments of Emergency Medicine,, Samsun, Turkey

Havva Sahin, MD

Ondokuz Mayis University, School of Medicine, Departments of Emergency Medicine,, Samsun, Turkey

Zahide Doganay, MD

Ondokuz Mayis University, School of Medicine, Departments of Emergency Medicine,, Samsun, Turkey

Hakan Guven, MD

Ondokuz Mayis University, School of Medicine, Departments of Emergency Medicine,, Samsun, Turkey

Yüksel Bek, PhD

Ondokuz Mayis University, School of Medicine, Departments of Biostatistics, Samsun, Turkey

Tekin Akpolat, MD

Ondokuz Mayis University, School of Medicine, Departments of Internal Medicine,, Samsun, Turkey

The aims of this study were to report experience in patients with organophosphate poisoning (OPP) and to discuss the potential role for hemoperfusion (HP) in the management of severe OPP. At the emergency service of a university hospital, 52 patients with acute OPP were included in this retrospective study. The patients were divided into 2 groups (Group 1, severe poisoning, n = 25; and Group 2, mild poisoning, n = 27). All patients with mild OPP survived. Seven patients (28%) of the 25 with severe OPP died. This study supports previous data documenting that HP is unnecessary in the management of mild OPP. Although there was not a control group (severe poisoning without HP treatment) in this study, experience suggests that HP can be useful in severe cases. Reports from centers having experience with severe OPP can help clarify this controversial issue. Randomized controlled (prospective) studies investigating the possible beneficial effects of HP on patient survival in patients with severe OPP with control group are needed.

Key Words: severe organophosphate poisoning • management • hemoperfusion

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?