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Bispectral Index Monitoring Documents Burst Suppression During Pentobarbital ComaDepartment of Anesthesiology and Department of Pediatrics, University of Missouri, Columbia, Missouri, Tobiasj{at}health.missouri.edu
During pentobarbital coma, electroencephalographic monitoring is used to document burst suppression (3-5 episodes of electrical activity/min). The current study evaluates the association of the bispectral index number and suppression ratio with a burst suppression pattern on electroencephalograph. The records of 7 patients (aged 2.9-14 years) who received pentobarbital for elevated intracranial pressure were retrospectively reviewed. The bispectral index number was 7 ± 5, 14 ± 3, and 37 ± 12, whereas the suppression ratio was 93 ± 7%, 75 ± 6%, and 29 ± 18% when the electroencephalograph showed
Key Words: pentobarbital coma • burst suppression • bispectral index • EEG monitoring • suppression ratio
This version was published on July
1, 2008 Journal of Intensive Care Medicine, Vol. 23, No. 4,
258-262 (2008) |
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2, 3-5, and 
6 bursts/min, respectively. The sensitivity and specificity of a bispectral index value of 10 to 20 were 96% and 92%, respectively, whereas the sensitivity and specificity of a suppression ratio of 65% to 85% were 89% and 88%, respectively, in demonstrating the presence of 3 to 5 bursts/min. Bispectral index monitoring may be easier to perform and may require less technical expertise to interpret.