SAGE Journals Online
Advertisement
Sign In to gain access to subscriptions and/or personal tools.

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Advertisement

Sign In to gain access to subscriptions and/or personal tools.
Journal of Intensive Care Medicine
This Article
Right arrow Full Text (OnlineFirst PDF)
Right arrow All Versions of this Article:
0885066608330098v1
24/2/122    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Varpula, T.
Right arrow Articles by Pettilä, V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Varpula, T.
Right arrow Articles by Pettilä, V.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Article

The Effects of Ventilatory Mode on Lung Aeration Assessed With Computer Tomography: A Randomized Control Study

Tero Varpula, MD, Ph.D.1*, Päivi Valta, MD, Ph.D.2, Antii Markkola, MD, Ph.D.3, Katrinna Pohjanen, MD4, Juha Halavaara, MD, Ph.D.5, Markku Hynynen, MD, Ph.D.5, and Ville Pettilä, MD, Ph.D.6

1 Jorvi Hospital, Helinki University Hospital, Intensive Care Unit
2 Anesthesiology Unit, Jorvi Hospital
3 Dept of Radiology
4 Hospital District of Helsinki and Uusimma
5 Department of Radiology
6 Intensive Care Units, Dept of Anesthesiology and ICM

* To whom correspondence should be addressed. E-mail: tero.varpula{at}hus.fi.


  Abstract

Maintenance of spontaneous breathing superimposed on mechanical ventilation is suggested to improve gas exchange in patients with acute lung injury. The aim of this study was to evaluate the long-term effects of airway pressure release ventilation with maintained unsupported spontaneous breathing (APRV) and synchronized intermittent mandatory ventilation with pressure support (SIMV) on the amount of lung collapse in acute lung injury patients. Thirty-seven patients with acute lung injury were studied in a trial comparing APRV or SIMV. Computer-assisted tomography scannings (CT) were performed before randomization and at day 7. The change in the amount of nonaerated lung was comparable between groups; 14.7% (3.8-17.4) in APRV group (n = 13) and 9.6% (-1.4 to 18.62) in the SIMV group (n = 10), (P = .65, difference in mean 4.9%, 95% confidence interval -9.0% to 19.0%). The effects of APRV and SIMV on lung aeration are similar after 7 days of mechanical ventilation.

First published on February 2, 2009, doi:10.1177/0885066608330098

Journal of Intensive Care Medicine 2009;24:122.

A more recent version of this article appeared on March 1, 2009

Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?




Advertisement